Introduction
Phyzyme® contains 6-phytase. It is authorised for use in the EU in piglets, pigs for fattening, sows, and various other species. Phyzyme® is available in dry and liquid forms.
Phyzyme® products: Phyzyme® XP 5000G (granulate) and Phyzyme XP 5000L (liquid)
Manufacturer´s main claims
Lowers the feed costs
Improves the environment
Technical specifications of Phyzyme® XP 5000G and L
EU category
Zootechnical additives
Functional group of additives
Digestibility enhancers
Active substance
(EC 3.1.3.26)
Phytase activity in the product
5000 FTU/g
EU approval, minimum content
For the animal categories below: 250 FTU/kg feed
Piglets (weaned)
Pigs for fattening
Chickens for fattening
Turkeys for fattening
Ducks for fattening
All avian species for fattening other than chickens, turkeys and ducks for fattening
All avian species reared for laying other than laying hens: 150 FTU/kg feed
Laying hens: 150 FTU/kg feed
Sows: 500 FTU/kg feed
End of period of EU authorisation
26 February 2030
EU code
4a1640
Production organism
Genetically modified Schizosaccharomyces pombe, ATCC 5233
Donor organisms
Escherichia coli
Product storage stability
XP 5000G: 12 months when stored in original packaging at 20°C; XP 5000L: 9 months when stored in original packaging at 20°C
Storage stability in premix and feed
XP 5000G remains stable for at least three months when mixed into feed or premixes and stored at 20°C. XP 5000L remains stable for at least three months when mixed into feed.
Heat stability
Rasmussen (2010) showed that Phyzyme XP is heat stable at high pelleting temperatures. A pelleting temperature at 95°C reduced the phytase activity by 13 %. It is advised to apply XP 5000L only post-pelleting
Carrier
L: Water, Sorbitol, Sodium chloride, Sodium citrate, Sodium benzoate, Potassium sorbate
P: Fermentation liquor, Sodium sulphate, Hydrated magnesium silicate, Starch, Polyvinyl alcohol
Package size
XP 5000G : 25 kg bags or 1000 kg big bagsXP 5000L : 200 or 1000 kg containers
Handling
The European Commission states: "For users of the additive and premixtures, feed business operators shall establish operational procedures and organisational measures to address potential risks resulting from its use. Where those risks cannot be eliminated or reduced to a minimum by such procedures and measures, the additive and premixtures shall be used with personal protective equipment, including breathing protection."
Manufacturer
IFF
List of references
EFSA (2008). Safety and efficacy of Phyzyme XP 10000 (TPT/L), 6-phytase, as a feed additive for chickens for fattening, laying hens, ducks for fattening, turkeys for fattening, piglets (weaned), pigs for fattening and sows. The EFSA Journal (2008) 915, 1-10
EU (2009). Commission Regulation (EC) No 379/2009 of 8 May 2009 concerning the authorisation of a new use of 6-phytase EC 3.1.3.26 as a feed additive for chickens for fattening, turkeys for fattening, laying hens, ducks for fattening, piglets (weaned), pigs for fattening and sows (holder of authorisation Danisco Animal Nutrition, legal entity Danisco (UK) Limited). Official Journal of the European Union, L 116/6
EU (2012). Commission Regulation (EU) No 840/2012 of 18 September 2012 concerning the authorisation of 6-phytase (EC 3.1.3.26) produced by Schizosaccharomyces pombe (ATCC 5233) as a feed additive for all avian species for fattening other than chickens for fattening, turkeys for fattening, and ducks for fattening and all avian species for laying other than laying hens (holder of the authorisation Danisco Animal Nutrition). L252/14-16
EU (2020). Commission Implementing Regulation (EU) No 2020/166 of 5 February 2020 concerning the renewal of the authorisation of 6-phytase produced by Schizosaccharomyces pombe (ATCC 5233) as a feed additive for chickens for fattening, laying hens, turkeys for fattening, ducks for fattening, weaned piglets, pigs for fattening and sows repealing Regulation (EC) No 785/2007 (holder of authorisation Danisco (UK) Ltd, trading as Danisco Animal Nutrition represented by Genencor B.V.). Official Journal of the European Union, L34/43-45
Rasmussen, D. K. (2010). Forskel i varmestabilitet for fytase og xylanaseprodukter i foder. Videncenter for Svineproduktion. Meddelelse nr. 875